Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models...
Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson’s disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Mitochondria-lysosome contacts are recently identified sites for mediating crosstalk between both organelles, but their role in normal and diseased human neurons remains unknown. In this study, we demonstrate that mitochondria-lysosome contacts can dynamically form in the soma, axons, and dendrites of human neurons, allowing for their bidirectional...
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Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_40982e38dcd44c1f9dff1e73b1f33d9a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_40982e38dcd44c1f9dff1e73b1f33d9a
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22113-3
