Targeting of retrovirus-derived Rtl8a / 8b causes late-onset obesity, reduced social response and in...
Targeting of retrovirus-derived Rtl8a / 8b causes late-onset obesity, reduced social response and increased apathy-like behaviour
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Publisher
England: The Royal Society
Journal title
Language
English
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Publication information
Publisher
England: The Royal Society
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Scope and Contents
Contents
Retrotransposon Gag-like (RTL) 8A, 8B and 8C are eutherian-specific genes derived from a certain retrovirus. They cluster as a triplet of genes on the X chromosome, but their function remains unknown. Here, we demonstrate that
Rtl8a
and
Rtl8b
play important roles in the brain: their double knockout (DKO) mice not only exhibit reduced so...
Alternative Titles
Full title
Targeting of retrovirus-derived Rtl8a / 8b causes late-onset obesity, reduced social response and increased apathy-like behaviour
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_40b11efd4b144dd2bff4b3000799b4eb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_40b11efd4b144dd2bff4b3000799b4eb
Other Identifiers
ISSN
2046-2441
E-ISSN
2046-2441
DOI
10.1098/rsob.240279
