DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid
DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Mycobacterium tuberculosis
is one of the global leading causes of death due to a single infectious agent. Pretomanid and delamanid are new antitubercular agents that have progressed through the drug discovery pipeline. These compounds are bicyclic nitroimidazoles that act as pro-drugs, requiring activation by a mycobacterial enzyme; however, the...
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DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid
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TN_cdi_doaj_primary_oai_doaj_org_article_40bdd0a34d744b8786bc6a3db7dc1740
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_40bdd0a34d744b8786bc6a3db7dc1740
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39300-z
