Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patie...
Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Systemic light chain amyloidosis (AL) is a life-threatening disease caused by aggregation and deposition of monoclonal immunoglobulin light chains (LC) in target organs. Severity of heart involvement is the most important factor determining prognosis. Here, we report the 4.0 Å resolution cryo-electron microscopy map and molecular model of amyloid...
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Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient
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TN_cdi_doaj_primary_oai_doaj_org_article_40c2c81167ec45c9bf6f9207f2cd41b5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_40c2c81167ec45c9bf6f9207f2cd41b5
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09133-w
