DNA damage response signatures are associated with frontline chemotherapy response and routes of tum...
DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer
About this item
Full title
Author / Creator
Morris, Benjamin B. , Heeke, Simon , Xi, Yuanxin , Diao, Lixia , Wang, Qi , Rocha, Pedro , Arriola, Edurne , Lee, Myung Chang , Tyson, Darren R. , Concannon, Kyle , Ramkumar, Kavya , Stewart, C. Allison , Cardnell, Robert J. , Wang, Runsheng , Quaranta, Vito , Wang, Jing , Heymach, John V. , Nabet, Barzin Y. , Shames, David S. , Gay, Carl M. and Byers, Lauren A.
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
A hallmark of small cell lung cancer (SCLC) is its recalcitrance to therapy. While most SCLCs respond to frontline therapy, resistance inevitably develops. Identifying phenotypes potentiating chemoresistance and immune evasion is a crucial unmet need. Previous reports have linked upregulation of the DNA damage response (DDR) machinery to chemoresis...
Alternative Titles
Full title
DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer
Authors, Artists and Contributors
Author / Creator
Heeke, Simon
Xi, Yuanxin
Diao, Lixia
Wang, Qi
Rocha, Pedro
Arriola, Edurne
Lee, Myung Chang
Tyson, Darren R.
Concannon, Kyle
Ramkumar, Kavya
Stewart, C. Allison
Cardnell, Robert J.
Wang, Runsheng
Quaranta, Vito
Wang, Jing
Heymach, John V.
Nabet, Barzin Y.
Shames, David S.
Gay, Carl M.
Byers, Lauren A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_40cbbde56bd748bbaf0c60f5ee08af9f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_40cbbde56bd748bbaf0c60f5ee08af9f
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-025-02291-0
