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Characterization of RNF144B and PPP2R2A identified by a novel approach using TCGA data in ovarian ca...

Characterization of RNF144B and PPP2R2A identified by a novel approach using TCGA data in ovarian ca...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_40f4098acf2d4477ac217b5b7c295c33

Characterization of RNF144B and PPP2R2A identified by a novel approach using TCGA data in ovarian cancer

About this item

Full title

Characterization of RNF144B and PPP2R2A identified by a novel approach using TCGA data in ovarian cancer

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2025-02, Vol.15 (1), p.5414-19

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

TCGA has identified predominant somatic copy number alterations (SCNA) affecting numerous genes in HGSOC. To identify cancer-driver genes from the regions of SCNA, we have devised a scoring system that integrates information from different genetic alterations. Applying this scoring system to the TCGA-HGSOC dataset (n = 316) we have identified sever...

Alternative Titles

Full title

Characterization of RNF144B and PPP2R2A identified by a novel approach using TCGA data in ovarian cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_40f4098acf2d4477ac217b5b7c295c33

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_40f4098acf2d4477ac217b5b7c295c33

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-76801-3

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