Combined homologous recombination repair deficiency and immune activation analysis for predicting in...
Combined homologous recombination repair deficiency and immune activation analysis for predicting intensified responses of anthracycline, cyclophosphamide and taxane chemotherapy in triple-negative breast cancer
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Author / Creator
Liao, Gaoming , Jiang, Zedong , Yang, Yiran , Zhang, Cong , Jiang, Meiting , Zhu, Jiali , Xu, Liwen , Xie, Aimin , Yan, Min , Zhang, Yunpeng , Xiao, Yun and Li, Xia
Publisher
London: BioMed Central Ltd
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Language
English
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Publication information
Publisher
London: BioMed Central Ltd
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Contents
Background Triple-negative breast cancer (TNBC) is a clinically aggressive disease with abundant variants that cause homologous recombination repair deficiency (HRD). Whether TNBC patients with HRD are sensitive to anthracycline, cyclophosphamide and taxane (ACT), and whether the combination of HRD and tumour immunity can improve the recognition of...
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Full title
Combined homologous recombination repair deficiency and immune activation analysis for predicting intensified responses of anthracycline, cyclophosphamide and taxane chemotherapy in triple-negative breast cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_410457d3743a4d70b9e56eb16ef6d7c6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_410457d3743a4d70b9e56eb16ef6d7c6
Other Identifiers
ISSN
1741-7015
E-ISSN
1741-7015
DOI
10.1186/s12916-021-02068-4
