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Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart fai...

Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart fai...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_412684d99061499fa5d90b956b7cff6b

Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart failure by secreting PDGF-BB

About this item

Full title

Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart failure by secreting PDGF-BB

Publisher

London: Nature Publishing Group UK

Journal title

Signal transduction and targeted therapy, 2022-07, Vol.7 (1), p.253-253, Article 253

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Recent studies have suggested that transplant of hiPS-CMs is a promising approach for treating heart failure. However, the optimally clinical benefits have been hampered by the immature nature of the hiPS-CMs, and the hiPS-CMs-secreted proteins contributing to the repair of cardiomyocytes remain largely unidentified. Here, we established a saponin<...

Alternative Titles

Full title

Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart failure by secreting PDGF-BB

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_412684d99061499fa5d90b956b7cff6b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_412684d99061499fa5d90b956b7cff6b

Other Identifiers

ISSN

2059-3635,2095-9907

E-ISSN

2059-3635

DOI

10.1038/s41392-022-01045-4

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