Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart fai...
Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart failure by secreting PDGF-BB
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Li, Hongmei , Wu, Fenfang , Huang, Guangrui , Wu, Di , Wang, Ting , Wang, Xiashuang , Wang, Kai , Feng, Yuyin and Xu, Anlong
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Recent studies have suggested that transplant of hiPS-CMs is a promising approach for treating heart failure. However, the optimally clinical benefits have been hampered by the immature nature of the hiPS-CMs, and the hiPS-CMs-secreted proteins contributing to the repair of cardiomyocytes remain largely unidentified. Here, we established a saponin<...
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Full title
Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart failure by secreting PDGF-BB
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TN_cdi_doaj_primary_oai_doaj_org_article_412684d99061499fa5d90b956b7cff6b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_412684d99061499fa5d90b956b7cff6b
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ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-022-01045-4