Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death
Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The endoplasmic reticulum, the cytoplasmic organelle that matures a massive amount of nascent secretory polypeptides, is particularly sensitive to stress. Endoplasmic reticulum stress causes unfolded proteins to populate the organelle, eliciting the unfolded protein response. During the unfolded protein response, GRP78—an endoplasmic reticulum mast...
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Full title
Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death
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TN_cdi_doaj_primary_oai_doaj_org_article_41562ffacfaf46d09359e93528290463
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41562ffacfaf46d09359e93528290463
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00029-1
