Development and Evaluation of Solid Dispersion-Based Sublingual Films of Nisoldipine
Development and Evaluation of Solid Dispersion-Based Sublingual Films of Nisoldipine
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Basel: MDPI AG
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Language
English
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Basel: MDPI AG
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Nisoldipine (NIS) is a calcium channel blocker that exhibits poor bioavailability (~5%) due to low aqueous solubility and presystemic metabolism in the gut wall. In this context, the present work aimed to develop NIS solid dispersion (NISSD)-based sublingual films using solvent casting technique to improve the dissolution. Phase solubility studies...
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Development and Evaluation of Solid Dispersion-Based Sublingual Films of Nisoldipine
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TN_cdi_doaj_primary_oai_doaj_org_article_418f963d74ac43a0a08a04d8fad85cbd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_418f963d74ac43a0a08a04d8fad85cbd
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ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph16111589
