IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmu...
IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Interleukin 35 (IL-35) is a heterodimeric cytokine composed of IL-12p35 and Ebi3 subunits. IL-35 suppresses autoimmune diseases while preventing host defense to infection and promoting tumor growth and metastasis by converting resting B and T cells into IL-10-producing and IL-35-producing regulatory B (Breg) and T (Treg) cells. Despite sharing the...
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IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease
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TN_cdi_doaj_primary_oai_doaj_org_article_4190c1c5e27f46209b8205b45199c5fa
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4190c1c5e27f46209b8205b45199c5fa
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00838-4
