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Loss of Homeostatic Microglia Signature in Prion Diseases

Loss of Homeostatic Microglia Signature in Prion Diseases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_419b6025cb1f4ed49b15a237a4d4f443

Loss of Homeostatic Microglia Signature in Prion Diseases

About this item

Full title

Loss of Homeostatic Microglia Signature in Prion Diseases

Publisher

Basel: MDPI AG

Journal title

Cells (Basel, Switzerland), 2022-09, Vol.11 (19), p.2948

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

Prion diseases are neurodegenerative diseases that affect humans and animals. They are always fatal and, to date, no treatment exists. The hallmark of prion disease pathophysiology is the misfolding of an endogenous protein, the cellular prion protein (PrPC), into its disease-associated isoform PrPSc. Besides the aggregation and deposition of misfo...

Alternative Titles

Full title

Loss of Homeostatic Microglia Signature in Prion Diseases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_419b6025cb1f4ed49b15a237a4d4f443

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_419b6025cb1f4ed49b15a237a4d4f443

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells11192948

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