Loss of Homeostatic Microglia Signature in Prion Diseases
Loss of Homeostatic Microglia Signature in Prion Diseases
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Basel: MDPI AG
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English
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Basel: MDPI AG
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Prion diseases are neurodegenerative diseases that affect humans and animals. They are always fatal and, to date, no treatment exists. The hallmark of prion disease pathophysiology is the misfolding of an endogenous protein, the cellular prion protein (PrPC), into its disease-associated isoform PrPSc. Besides the aggregation and deposition of misfo...
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Loss of Homeostatic Microglia Signature in Prion Diseases
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TN_cdi_doaj_primary_oai_doaj_org_article_419b6025cb1f4ed49b15a237a4d4f443
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_419b6025cb1f4ed49b15a237a4d4f443
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells11192948