Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVI...
Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID-19
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Despite recent therapeutic advances, combating cancer resistance remains a formidable challenge. The 78-kilodalton glucose-regulated protein (GRP78), a key stress-inducible endoplasmic reticulum (ER) chaperone, plays a crucial role in both cancer cell survival and stress adaptation. GRP78 is also upregulated during SARS-CoV-2 infection and acts as...
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Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID-19
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TN_cdi_doaj_primary_oai_doaj_org_article_41b097963d3a4f95bc528fc71d41ad9c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41b097963d3a4f95bc528fc71d41ad9c
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ISSN
2045-3701
E-ISSN
2045-3701
DOI
10.1186/s13578-024-01297-3
