Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendr...
Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice
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Author / Creator
Papaioannou, Nikos E. , Salei, Natallia , Rambichler, Stephan , Ravi, Kaushikk , Popovic, Jelena , Küntzel, Vanessa , Lehmann, Christian H. K. , Fiancette, Remi , Salvermoser, Johanna , Gajdasik, Dominika W. , Mettler, Ramona , Messerer, Denise , Carrelha, Joana , Ohnmacht, Caspar , Haller, Dirk , Stumm, Ralf , Straub, Tobias , Jacobsen, Sten Eirik W. , Schulz, Christian , Withers, David R. , Schotta, Gunnar , Dudziak, Diana and Schraml, Barbara U.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Conventional dendritic cells (cDC) are key activators of naive T cells, and can be targeted in adults to induce adaptive immunity, but in early life are considered under-developed or functionally immature. Here we show that, in early life, when the immune system develops, cDC2 exhibit a dual hematopoietic origin and, like other myeloid and lymphoid...
Alternative Titles
Full title
Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice
Authors, Artists and Contributors
Author / Creator
Salei, Natallia
Rambichler, Stephan
Ravi, Kaushikk
Popovic, Jelena
Küntzel, Vanessa
Lehmann, Christian H. K.
Fiancette, Remi
Salvermoser, Johanna
Gajdasik, Dominika W.
Mettler, Ramona
Messerer, Denise
Carrelha, Joana
Ohnmacht, Caspar
Haller, Dirk
Stumm, Ralf
Straub, Tobias
Jacobsen, Sten Eirik W.
Schulz, Christian
Withers, David R.
Schotta, Gunnar
Dudziak, Diana
Schraml, Barbara U.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_41e3849697dd487fb5c3e7640b8e444b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41e3849697dd487fb5c3e7640b8e444b
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20659-2
