Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing...
Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis
About this item
Full title
Author / Creator
Penkava, Frank , Velasco-Herrera, Martin Del Castillo , Young, Matthew D. , Yager, Nicole , Nwosu, Lilian N. , Pratt, Arthur G. , Lara, Alicia Lledo , Guzzo, Charlotte , Maroof, Ash , Mamanova, Lira , Cole, Suzanne , Efremova, Mirjana , Simone, Davide , Filer, Andrew , Brown, Chrysothemis C. , Croxford, Andrew L. , Isaacs, John D. , Teichmann, Sarah , Bowness, Paul , Behjati, Sam and Hussein Al-Mossawi, M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Psoriatic arthritis (PsA) is a debilitating immune-mediated inflammatory arthritis of unknown pathogenesis commonly affecting patients with skin psoriasis. Here we use complementary single-cell approaches to study leukocytes from PsA joints. Mass cytometry demonstrates a 3-fold expansion of memory CD8 T cells in the joints of PsA patients compared...
Alternative Titles
Full title
Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis
Authors, Artists and Contributors
Author / Creator
Velasco-Herrera, Martin Del Castillo
Young, Matthew D.
Yager, Nicole
Nwosu, Lilian N.
Pratt, Arthur G.
Lara, Alicia Lledo
Guzzo, Charlotte
Maroof, Ash
Mamanova, Lira
Cole, Suzanne
Efremova, Mirjana
Simone, Davide
Filer, Andrew
Brown, Chrysothemis C.
Croxford, Andrew L.
Isaacs, John D.
Teichmann, Sarah
Bowness, Paul
Behjati, Sam
Hussein Al-Mossawi, M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_41e60fd553ac455d9a90df903aa0ed85
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41e60fd553ac455d9a90df903aa0ed85
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18513-6
