Biomarkers predictive of response to pembrolizumab in head and neck cancer
Biomarkers predictive of response to pembrolizumab in head and neck cancer
About this item
Full title
Author / Creator
Pfister, David G. , Haddad, Robert I. , Worden, Francis P. , Weiss, Jared , Mehra, Ranee , Chow, Laura Q. M. , Liu, Stephen V. , Kang, Hyunseok , Saba, Nabil F. , Wirth, Lori J. , Sukari, Ammar , Massarelli, Erminia , Ayers, Mark , Albright, Andrew , Webber, Andrea L. , Mogg, Robin , Lunceford, Jared , Huang, Lingkang , Cristescu, Razvan , Cheng, Jonathan , Seiwert, Tanguy Y. and Bauml, Joshua M.
Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Background
We performed an integrated biomarker evaluation in pembrolizumab‐treated patients with R/M HNSCC enrolled in KEYNOTE‐012 or KEYNOTE‐055. The relationship between biomarkers and HPV status was explored.
Methods
We evaluated PD‐L1 (combined positive score [CPS]), TMB, T‐cell‐inflamed gene expression profile (TcellinfGEP), and HPV...
Alternative Titles
Full title
Biomarkers predictive of response to pembrolizumab in head and neck cancer
Authors, Artists and Contributors
Author / Creator
Haddad, Robert I.
Worden, Francis P.
Weiss, Jared
Mehra, Ranee
Chow, Laura Q. M.
Liu, Stephen V.
Kang, Hyunseok
Saba, Nabil F.
Wirth, Lori J.
Sukari, Ammar
Massarelli, Erminia
Ayers, Mark
Albright, Andrew
Webber, Andrea L.
Mogg, Robin
Lunceford, Jared
Huang, Lingkang
Cristescu, Razvan
Cheng, Jonathan
Seiwert, Tanguy Y.
Bauml, Joshua M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_41ead9902e374b769caeb779819059f4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_41ead9902e374b769caeb779819059f4
Other Identifiers
ISSN
2045-7634
E-ISSN
2045-7634
DOI
10.1002/cam4.5434
