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Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level

Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4221444650b74227b0be0661a1952aaf

Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level

About this item

Full title

Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-04, Vol.11 (1), p.8032-17, Article 8032

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mammalian cytosine DNA methylation (5mC) is associated with the integrity of the genome and the transcriptional status of nuclear DNA. Due to technical limitations, it has been less clear if mitochondrial DNA (mtDNA) is methylated and whether 5mC has a regulatory role in this context. Here, we used bisulfite-independent single-molecule sequencing o...

Alternative Titles

Full title

Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4221444650b74227b0be0661a1952aaf

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4221444650b74227b0be0661a1952aaf

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-87457-8

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