Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level
Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Mammalian cytosine DNA methylation (5mC) is associated with the integrity of the genome and the transcriptional status of nuclear DNA. Due to technical limitations, it has been less clear if mitochondrial DNA (mtDNA) is methylated and whether 5mC has a regulatory role in this context. Here, we used bisulfite-independent single-molecule sequencing o...
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Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level
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TN_cdi_doaj_primary_oai_doaj_org_article_4221444650b74227b0be0661a1952aaf
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4221444650b74227b0be0661a1952aaf
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-87457-8