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Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesion...

Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesion...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_42a72dde94804cbaafa23cc1ebad1ef5

Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions

About this item

Full title

Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions

Publisher

England: BioMed Central Ltd

Journal title

Journal of neuroinflammation, 2022-10, Vol.19 (1), p.256-14, Article 256

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Previous studies have demonstrated that purinergic receptors could be therapeutic targets to modulate the inflammatory response in multiple models of brain diseases. However, tools for the selective and efficient targeting of these receptors are lacking. The development of new P2X7-specific nanobodies (nbs) has enabled us to effectively block the P...

Alternative Titles

Full title

Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_42a72dde94804cbaafa23cc1ebad1ef5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_42a72dde94804cbaafa23cc1ebad1ef5

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/s12974-022-02601-z

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