Recapitulating Parkinson's disease pathology in a three-dimensional human neural cell culture model
Recapitulating Parkinson's disease pathology in a three-dimensional human neural cell culture model
About this item
Full title
Author / Creator
Publisher
England: The Company of Biologists Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: The Company of Biologists Ltd
Subjects
More information
Scope and Contents
Contents
Extensive loss of dopaminergic neurons and aggregation of the protein α-synuclein into ubiquitin-positive Lewy bodies represents a major neuropathological hallmark of Parkinson's disease (PD). At present, the generation of large nuclear-associated Lewy bodies from endogenous wild-type α-synuclein, translationally regulated under its own promoter in...
Alternative Titles
Full title
Recapitulating Parkinson's disease pathology in a three-dimensional human neural cell culture model
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_42b8eb5ea8f5428785fecf6ccddb50fa
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_42b8eb5ea8f5428785fecf6ccddb50fa
Other Identifiers
ISSN
1754-8403,1754-8411
E-ISSN
1754-8411
DOI
10.1242/dmm.038042
