Attenuation of Nicotine Effects on A549 Lung Cancer Cells by Synthetic α7 nAChR Antagonists APS7-2 a...
Attenuation of Nicotine Effects on A549 Lung Cancer Cells by Synthetic α7 nAChR Antagonists APS7-2 and APS8-2
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Nicotine binds to nicotinic acetylcholine receptors (nAChRs) that are overexpressed in different cancer cells, promoting tumor growth and resistance to chemotherapy. In this study, we aimed to investigate the potential of APS7-2 and APS8-2, synthetic analogs of a marine sponge toxin, to inhibit nicotine-mediated effects on A549 human lung cancer ce...
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Attenuation of Nicotine Effects on A549 Lung Cancer Cells by Synthetic α7 nAChR Antagonists APS7-2 and APS8-2
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TN_cdi_doaj_primary_oai_doaj_org_article_42d0f47ed1724abdaaa70fd7aa45ffa1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_42d0f47ed1724abdaaa70fd7aa45ffa1
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ISSN
1660-3397
E-ISSN
1660-3397
DOI
10.3390/md22040147
