Cas12a-assisted precise targeted cloning using in vivo Cre-lox recombination
Cas12a-assisted precise targeted cloning using in vivo Cre-lox recombination
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Direct cloning represents the most efficient strategy to access the vast number of uncharacterized natural product biosynthetic gene clusters (BGCs) for the discovery of novel bioactive compounds. However, due to their large size, repetitive nature, or high GC-content, large-scale cloning of these BGCs remains an overwhelming challenge. Here, we re...
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Cas12a-assisted precise targeted cloning using in vivo Cre-lox recombination
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TN_cdi_doaj_primary_oai_doaj_org_article_42e3dde80df44f6a95cfb8762a0ff62b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_42e3dde80df44f6a95cfb8762a0ff62b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21275-4
