N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote hear...
N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote heart regeneration
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Author / Creator
Ma, Wenya , Tian, Yanan , Shi, Leping , Liang, Jing , Ouyang, Qimeng , Li, Jianglong , Chen, Hongyang , Sun, Hongyue , Ji, Haoyu , Liu, Xu , Huang, Wei , Gao, Xinlu , Jin, Xiaoyan , Wang, Xiuxiu , Liu, Yining , Yu, Yang , Guo, Xiaofei , Tian, Ye , Yang, Fan , Li, Faqian , Wang, Ning and Cai, Benzhi
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Translational control is crucial for protein production in various biological contexts. Here, we use Ribo-seq and RNA-seq to show that genes related to oxidative phosphorylation are translationally downregulated during heart regeneration. We find that Nat10 regulates the expression of Uqcr11 and Uqcrb mRNAs in mouse and human cardiomyocytes. In mic...
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Full title
N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote heart regeneration
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TN_cdi_doaj_primary_oai_doaj_org_article_42fb7334384e46d5a6c07d984296926e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_42fb7334384e46d5a6c07d984296926e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-46458-7
