Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer p...
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Tumor-associated macrophages (TAMs) are key regulators of the complex interplay between cancer and the immune microenvironment. Tumor cell-derived spondin 2 (SPON2) is an extracellular matrix glycoprotein that has complicated roles in recruitment of macrophages and neutrophils during inflammation. Overexpression of SPON2 has been shown to promote t...
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Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC
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TN_cdi_doaj_primary_oai_doaj_org_article_431411549d9c4db3983cd3fcdca9e855
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_431411549d9c4db3983cd3fcdca9e855
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-021-02108-0
