Translesion activity of PrimPol on DNA with cisplatin and DNA–protein cross-links
Translesion activity of PrimPol on DNA with cisplatin and DNA–protein cross-links
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Human PrimPol belongs to the archaeo-eukaryotic primase superfamily of primases and is involved in de novo DNA synthesis downstream of blocking DNA lesions and non-B DNA structures. PrimPol possesses both DNA/RNA primase and DNA polymerase activities, and also bypasses a number of DNA lesions in vitro. In this work, we have analyzed translesion syn...
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Translesion activity of PrimPol on DNA with cisplatin and DNA–protein cross-links
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TN_cdi_doaj_primary_oai_doaj_org_article_4385708681084e81aa35235773846c76
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4385708681084e81aa35235773846c76
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-96692-y
