Optimizing rabies mRNA vaccine efficacy via RABV-G structural domain screening and heterologous prim...
Optimizing rabies mRNA vaccine efficacy via RABV-G structural domain screening and heterologous prime-boost immunization
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Author / Creator
Li, Dongdong , Wang, Xuan , Li, Gaotian , Zhou, Jingying , Bian, Lijun , Zhao, Xiaoyan , Xing, Liao , Zeng, Juanmei , Cui, Jiaxing , Cui, Lili , Zhang, Yong and Chen, Yan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
mRNA vaccine has become a promising technology platform for rabies prevention. This study explores the roles of different structural domains of rabies virus glycoprotein (RABV-G) and heterologous prime-boost strategies for enhanced immune responses and protection. The results suggested that mRNA vaccines encoding full-length RABV-G (RABV-Full) and...
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Full title
Optimizing rabies mRNA vaccine efficacy via RABV-G structural domain screening and heterologous prime-boost immunization
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4391c42f70a74cd08f64714ae6211b5f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4391c42f70a74cd08f64714ae6211b5f
Other Identifiers
ISSN
2059-0105
E-ISSN
2059-0105
DOI
10.1038/s41541-025-01098-w
