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Glycolytic disruption restricts Drosophila melanogaster larval growth via the cytokine Upd3

Glycolytic disruption restricts Drosophila melanogaster larval growth via the cytokine Upd3

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_43977f5db57d4fe5afc56a3023d01733

Glycolytic disruption restricts Drosophila melanogaster larval growth via the cytokine Upd3

About this item

Full title

Glycolytic disruption restricts Drosophila melanogaster larval growth via the cytokine Upd3

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2025-05, Vol.21 (5), p.e1011690

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Drosophila larval growth requires efficient conversion of dietary nutrients into biomass. Lactate dehydrogenase (Ldh) and glycerol-3-phosphate dehydrogenase (Gpdh1) support this larval metabolic program by cooperatively promoting glycolytic flux. Consistent with their cooperative functions, the loss of both enzymes, but not either single enzyme alo...

Alternative Titles

Full title

Glycolytic disruption restricts Drosophila melanogaster larval growth via the cytokine Upd3

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_43977f5db57d4fe5afc56a3023d01733

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_43977f5db57d4fe5afc56a3023d01733

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1011690

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