Mechanical Force‐Induced cGAS Activation in Carcinoma Cells Facilitates Splenocytes into Liver to Dr...
Mechanical Force‐Induced cGAS Activation in Carcinoma Cells Facilitates Splenocytes into Liver to Drive Metastasis
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Author / Creator
Zhang, Xurui , Huang, Na , Mu, Yanhua , Chen, Haiyan , Zhu, Mengchen , Zhang, Shaoying , Liu, Pengfei , Zhang, Hailong , Deng, Huan , Feng, Keping , Shang, Qi , Liu, Xi , Zhang, Chen , Shi, Mengjiao , Yang, Lan , Sun, Jin , Kong, Guangyao , Geng, Jing , Lu, Shemin and Li, Zongfang
Publisher
Germany: John Wiley & Sons, Inc
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Language
English
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Publisher
Germany: John Wiley & Sons, Inc
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Contents
Liver metastasis is the main cause of cancer‐related mortality. During the metastasis process, circulating carcinoma cells hardly pass through narrow capillaries, leading to nuclear deformation. However, the effects of nuclear deformation and its underlying mechanisms on metastasis need further study. Here, it is shown that mechanical force‐induced...
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Full title
Mechanical Force‐Induced cGAS Activation in Carcinoma Cells Facilitates Splenocytes into Liver to Drive Metastasis
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TN_cdi_doaj_primary_oai_doaj_org_article_43afa7b02d2a4263a6178154f35d19d4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_43afa7b02d2a4263a6178154f35d19d4
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ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202401127