HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
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Author / Creator
Mawambo, Gaëlle , Oubaha, Malika , Ichiyama, Yusuke , Blot, Guillaume , Crespo-Garcia, Sergio , Dejda, Agnieszka , Binet, François , Diaz-Marin, Roberto , Sawchyn, Christina , Sergeev, Mikhail , Juneau, Rachel , Kaufman, Randal J , Affar, El Bachir , Mallette, Frédérick A , Wilson, Ariel M and Sapieha, Przemyslaw
Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Scope and Contents
Contents
Cellular adaptation to low oxygen tension triggers primitive pathways that ensure proper cell function. Conditions of hypoxia and low glucose are characteristic of injured tissues and hence successive waves of inflammatory cells must be suited to function under low oxygen tension and metabolic stress. While Hypoxia-Inducible Factor (HIF)-1α has bee...
Alternative Titles
Full title
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
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TN_cdi_doaj_primary_oai_doaj_org_article_43e12a5532544c0686ece219c67a0571
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_43e12a5532544c0686ece219c67a0571
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-023-02793-y