Phenothiazines Enhance Mild Hypothermia-induced Neuroprotection via PI3K/Akt Regulation in Experimen...
Phenothiazines Enhance Mild Hypothermia-induced Neuroprotection via PI3K/Akt Regulation in Experimental Stroke
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An, Hong , Duan, Yunxia , Wu, Di , Yip, James , Elmadhoun, Omar , Wright, Joshua C. , Shi, Wenjuan , Liu, Kaiyin , He, Xiaoduo , Shi, Jingfei , Jiang, Fang , Ji, Xunming and Ding, Yuchuan
Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Physical hypothermia has long been considered a promising neuroprotective treatment of ischemic stroke, but the treatment’s various complications along with the impractical duration and depth of therapy significantly narrow its clinical scope. In the present study, the model of reversible right middle cerebral artery occlusion (MCAO) for 2 h was us...
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Full title
Phenothiazines Enhance Mild Hypothermia-induced Neuroprotection via PI3K/Akt Regulation in Experimental Stroke
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TN_cdi_doaj_primary_oai_doaj_org_article_43ed0bf086ca49439ce752cf2b58ae76
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_43ed0bf086ca49439ce752cf2b58ae76
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-06752-5