Multiscale Model of Antiviral Timing, Potency, and Heterogeneity Effects on an Epithelial Tissue Pat...
Multiscale Model of Antiviral Timing, Potency, and Heterogeneity Effects on an Epithelial Tissue Patch Infected by SARS-CoV-2
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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We extend our established agent-based multiscale computational model of infection of lung tissue by SARS-CoV-2 to include pharmacokinetic and pharmacodynamic models of remdesivir. We model remdesivir treatment for COVID-19; however, our methods are general to other viral infections and antiviral therapies. We investigate the effects of drug potency...
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Full title
Multiscale Model of Antiviral Timing, Potency, and Heterogeneity Effects on an Epithelial Tissue Patch Infected by SARS-CoV-2
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TN_cdi_doaj_primary_oai_doaj_org_article_43f419d2c0814c62b25220c56a626307
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_43f419d2c0814c62b25220c56a626307
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ISSN
1999-4915
E-ISSN
1999-4915
DOI
10.3390/v14030605
