Tissue-specific modifier alleles determine Mertk loss-of-function traits
Tissue-specific modifier alleles determine Mertk loss-of-function traits
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Author / Creator
Akalu, Yemsratch T , Mercau, Maria E , Ansems, Marleen , Hughes, Lindsey D , Nevin, James , Alberto, Emily J , Liu, Xinran N , He, Li-Zhen , Alvarado, Diego , Keler, Tibor , Kong, Yong , Philbrick, William M , Bosenberg, Marcus , Finnemann, Silvia C , Iavarone, Antonio , Lasorella, Anna , Rothlin, Carla V and Ghosh, Sourav
Publisher
England: eLife Sciences Publications Ltd
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English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
Knockout (KO) mouse models play critical roles in elucidating biological processes behind disease-associated or disease-resistant traits. As a presumed consequence of gene KO, mice display certain phenotypes. Based on insight into the molecular role of said gene in a biological process, it is inferred that the particular biological process causally...
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Tissue-specific modifier alleles determine Mertk loss-of-function traits
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TN_cdi_doaj_primary_oai_doaj_org_article_43fad56f4e26479584968f8d6e15f037
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_43fad56f4e26479584968f8d6e15f037
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.80530