A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers
A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
Precision medicine therapies require identification of unique molecular cancer characteristics. Hexokinase (HK) activity has been proposed as a therapeutic target; however, different hexokinase isoforms have not been well characterized as alternative targets. While HK2 is highly expressed in the majority of cancers, cancer subtypes with differentia...
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Full title
A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers
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TN_cdi_doaj_primary_oai_doaj_org_article_440363d204aa4ccf82544f27f7fe42b8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_440363d204aa4ccf82544f27f7fe42b8
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ISSN
2049-3002
E-ISSN
2049-3002
DOI
10.1186/s40170-018-0181-8