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A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers

A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_440363d204aa4ccf82544f27f7fe42b8

A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers

About this item

Full title

A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers

Publisher

England: BioMed Central Ltd

Journal title

Cancer & metabolism, 2018-06, Vol.6 (1), p.7-7, Article 7

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Precision medicine therapies require identification of unique molecular cancer characteristics. Hexokinase (HK) activity has been proposed as a therapeutic target; however, different hexokinase isoforms have not been well characterized as alternative targets. While HK2 is highly expressed in the majority of cancers, cancer subtypes with differentia...

Alternative Titles

Full title

A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_440363d204aa4ccf82544f27f7fe42b8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_440363d204aa4ccf82544f27f7fe42b8

Other Identifiers

ISSN

2049-3002

E-ISSN

2049-3002

DOI

10.1186/s40170-018-0181-8

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