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Effects of genetic deletion versus pharmacological blockade of the LPA1 receptor on depression-like...

Effects of genetic deletion versus pharmacological blockade of the LPA1 receptor on depression-like...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4403fd2e5f9a464989c57c0b6fd772d6

Effects of genetic deletion versus pharmacological blockade of the LPA1 receptor on depression-like behaviour and related brain functional activity

About this item

Full title

Effects of genetic deletion versus pharmacological blockade of the LPA1 receptor on depression-like behaviour and related brain functional activity

Publisher

Cambridge: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2018-09, Vol.11 (9)

Language

English

Formats

Publication information

Publisher

Cambridge: The Company of Biologists Ltd

More information

Scope and Contents

Contents

Animal models of psychopathology are particularly useful for studying the neurobiology of depression and characterising the subtypes. Recently, our group was the first to identify a possible relationship between the LPA1 receptor and a mixed anxiety-depression phenotype. Specifically, maLPA1-null mice exhibited a phenotype characterised by depressi...

Alternative Titles

Full title

Effects of genetic deletion versus pharmacological blockade of the LPA1 receptor on depression-like behaviour and related brain functional activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4403fd2e5f9a464989c57c0b6fd772d6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4403fd2e5f9a464989c57c0b6fd772d6

Other Identifiers

ISSN

1754-8403

E-ISSN

1754-8411

DOI

10.1242/dmm.035519

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