PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disea...
PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Huntington disease (HD) is an inherited neurodegenerative disease caused by an abnormal expansion of a CAG repeat in the huntingtin HTT (HD) gene. The primary genetic determinant of the age at onset (AO) is the length of the HTT CAG repeat; however, the remaining genetic contribution to the AO of HD has largely not been elucidated. Recent studies s...
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Full title
PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease
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TN_cdi_doaj_primary_oai_doaj_org_article_4425634951c24054bec1d06e2015d5b5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4425634951c24054bec1d06e2015d5b5
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/1750-1326-6-32
