Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory suppo...
Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis
About this item
Full title
Author / Creator
Maiques, Oscar , Sallan, Marta C. , Laddach, Roman , Pandya, Pahini , Varela, Adrian , Crosas-Molist, Eva , Barcelo, Jaume , Courbot, Olivia , Liu, Yanbo , Graziani, Vittoria , Arafat, Youssef , Sewell, Joanne , Rodriguez-Hernandez, Irene , Fanshawe, Bruce , Jung-Garcia, Yaiza , Imbert, Paul RC , Grasset, Eloise M. , Albrengues, Jean , Santacana, Maria , Macià, Anna , Tarragona, Jordi , Matias-Guiu, Xavier , Marti, Rosa M. , Tsoka, Sophia , Gaggioli, Cedric , Orgaz, Jose L. , Fruhwirth, Gilbert O. , Wallberg, Fredrik , Betteridge, Kai , Reyes-Aldasoro, Constantino Carlos , Haider, Syed , Braun, Andrejs , Karagiannis, Sophia N. , Elosegui-Artola, Alberto and Sanz-Moreno, Victoria
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The extracellular matrix (ECM) controls tumour dissemination. We characterise ECM organization in human and mouse tumours, identifying three regions: tumour body, proximal invasive front and distal invasive front. Invasive areas show increased matrix density, fibre thickness, length, and alignment, with unique radial fibre orientation at the distal...
Alternative Titles
Full title
Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis
Authors, Artists and Contributors
Author / Creator
Sallan, Marta C.
Laddach, Roman
Pandya, Pahini
Varela, Adrian
Crosas-Molist, Eva
Barcelo, Jaume
Courbot, Olivia
Liu, Yanbo
Graziani, Vittoria
Arafat, Youssef
Sewell, Joanne
Rodriguez-Hernandez, Irene
Fanshawe, Bruce
Jung-Garcia, Yaiza
Imbert, Paul RC
Grasset, Eloise M.
Albrengues, Jean
Santacana, Maria
Macià, Anna
Tarragona, Jordi
Matias-Guiu, Xavier
Marti, Rosa M.
Tsoka, Sophia
Gaggioli, Cedric
Orgaz, Jose L.
Fruhwirth, Gilbert O.
Wallberg, Fredrik
Betteridge, Kai
Reyes-Aldasoro, Constantino Carlos
Haider, Syed
Braun, Andrejs
Karagiannis, Sophia N.
Elosegui-Artola, Alberto
Sanz-Moreno, Victoria
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_442e1924b7c647cf84fc76d1eeba157c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_442e1924b7c647cf84fc76d1eeba157c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-56299-7
