Preclinical assessment of drug–drug interaction of fb‐PMT, a novel anti‐cancer thyrointegrin αvβ3 an...
Preclinical assessment of drug–drug interaction of fb‐PMT, a novel anti‐cancer thyrointegrin αvβ3 antagonist
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United States: John Wiley & Sons, Inc
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Language
English
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United States: John Wiley & Sons, Inc
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The objective of the current study was to identify potential drug–drug interactions (DDIs) with the drug candidate fb‐PMT, a novel anticancer thyrointegrin αvß3 antagonist. This was accomplished by using several in vitro assays to study interactions of fb‐PMT with both cytochrome P450 (CYP) enzymes and drug transporters, two common mechanisms leadi...
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Preclinical assessment of drug–drug interaction of fb‐PMT, a novel anti‐cancer thyrointegrin αvβ3 antagonist
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TN_cdi_doaj_primary_oai_doaj_org_article_442f979fd53f48b787fe4e6b8a1cad97
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_442f979fd53f48b787fe4e6b8a1cad97
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ISSN
1752-8054
E-ISSN
1752-8062
DOI
10.1111/cts.13504