Collective forces of tumor spheroids in three-dimensional biopolymer networks
Collective forces of tumor spheroids in three-dimensional biopolymer networks
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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We describe a method for quantifying the contractile forces that tumor spheroids collectively exert on highly nonlinear three-dimensional collagen networks. While three-dimensional traction force microscopy for single cells in a nonlinear matrix is computationally complex due to the variable cell shape, here we exploit the spherical symmetry of tum...
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Collective forces of tumor spheroids in three-dimensional biopolymer networks
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TN_cdi_doaj_primary_oai_doaj_org_article_445809e39596411894c241e66afcfafe
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_445809e39596411894c241e66afcfafe
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.51912