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Collective forces of tumor spheroids in three-dimensional biopolymer networks

Collective forces of tumor spheroids in three-dimensional biopolymer networks

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_445809e39596411894c241e66afcfafe

Collective forces of tumor spheroids in three-dimensional biopolymer networks

About this item

Full title

Collective forces of tumor spheroids in three-dimensional biopolymer networks

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2020-04, Vol.9

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

We describe a method for quantifying the contractile forces that tumor spheroids collectively exert on highly nonlinear three-dimensional collagen networks. While three-dimensional traction force microscopy for single cells in a nonlinear matrix is computationally complex due to the variable cell shape, here we exploit the spherical symmetry of tum...

Alternative Titles

Full title

Collective forces of tumor spheroids in three-dimensional biopolymer networks

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_445809e39596411894c241e66afcfafe

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_445809e39596411894c241e66afcfafe

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.51912

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