Reductive nanocomplex encapsulation of cRGD-siRNA conjugates for enhanced targeting to cancer cells
Reductive nanocomplex encapsulation of cRGD-siRNA conjugates for enhanced targeting to cancer cells
About this item
Full title
Author / Creator
Zhou, Zhaoxiu , Liu, Shuang , Zhang, Yanfen , Yang, Xiaotao , Ma, Yuan , Guan, Zhu , Wu, Yun , Zhang, Lihe and Yang, Zhenjun
Publisher
New Zealand: Dove Medical Press Limited
Journal title
Language
English
Formats
Publication information
Publisher
New Zealand: Dove Medical Press Limited
Subjects
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Scope and Contents
Contents
In this study, through covalent conjugation and lipid material entrapment, a combined modification strategy was established for effective delivery of small interfering RNA (siRNA). Single strands of siRNA targeting to
gene (siMB3) conjugated with cRGD peptide at 3'-terminus or 5'-terminus via cleavable disulfide bond was synthesized and then ann...
Alternative Titles
Full title
Reductive nanocomplex encapsulation of cRGD-siRNA conjugates for enhanced targeting to cancer cells
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_446a62b388f04beabe84b81744f88dad
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_446a62b388f04beabe84b81744f88dad
Other Identifiers
ISSN
1178-2013,1176-9114
E-ISSN
1178-2013
DOI
10.2147/IJN.S136726
