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RANKL regulates male reproductive function

RANKL regulates male reproductive function

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_449cfadef8624b1985ea27a0de2d651b

RANKL regulates male reproductive function

About this item

Full title

RANKL regulates male reproductive function

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-04, Vol.12 (1), p.2450-15, Article 2450

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Infertile men have few treatment options. Here, we demonstrate that the transmembrane receptor activator of NF-kB ligand (RANKL) signaling system is active in mouse and human testis. RANKL is highly expressed in Sertoli cells and signals through RANK, expressed in most germ cells, whereas the RANKL-inhibitor osteoprotegerin (OPG) is expressed in ge...

Alternative Titles

Full title

RANKL regulates male reproductive function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_449cfadef8624b1985ea27a0de2d651b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_449cfadef8624b1985ea27a0de2d651b

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-22734-8

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