METTL3-mediated m6A modification of SIRT1 mRNA affects the progression of diabetic cataracts through...
METTL3-mediated m6A modification of SIRT1 mRNA affects the progression of diabetic cataracts through cellular autophagy and senescence
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Author / Creator
Dong, Su , Zhang, Jiajia , Fu, Yushan , Tang, Gege , Chen, Jianfeng , Sun, Dawei , Qi, Yanhua and Zhou, Nan
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The increasing incidence of diabetes mellitus has established diabetic cataracts (DC) as a significant worldwide public health issue. The mechanisms underlying DC remain unknown, and effective prevention and treatment strategies are lacking. Accordingly, we aimed to explore the role and mechanism behind N6-methyladenosine (m6A) in DC progression.
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Full title
METTL3-mediated m6A modification of SIRT1 mRNA affects the progression of diabetic cataracts through cellular autophagy and senescence
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TN_cdi_doaj_primary_oai_doaj_org_article_44abc2921c7e44cb86e9859eea78c7c6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_44abc2921c7e44cb86e9859eea78c7c6
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ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-024-05691-w