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Insights into a Cancer-Target Demethylase: Substrate Prediction through Systematic Specificity Analy...

Insights into a Cancer-Target Demethylase: Substrate Prediction through Systematic Specificity Analy...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_44cb37f32494409d887cd64c8ec52349

Insights into a Cancer-Target Demethylase: Substrate Prediction through Systematic Specificity Analysis for KDM3A

About this item

Full title

Insights into a Cancer-Target Demethylase: Substrate Prediction through Systematic Specificity Analysis for KDM3A

Publisher

Switzerland: MDPI AG

Journal title

Biomolecules (Basel, Switzerland), 2022-04, Vol.12 (5), p.641

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Jumonji C (JmjC) lysine demethylases (KDMs) catalyze the removal of methyl (-CH
) groups from modified lysyl residues. Several JmjC KDMs promote cancerous properties and these findings have primarily been in relation to histone demethylation. However, the biological roles of these enzymes are increasingly being shown to also be attributed to non...

Alternative Titles

Full title

Insights into a Cancer-Target Demethylase: Substrate Prediction through Systematic Specificity Analysis for KDM3A

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_44cb37f32494409d887cd64c8ec52349

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_44cb37f32494409d887cd64c8ec52349

Other Identifiers

ISSN

2218-273X

E-ISSN

2218-273X

DOI

10.3390/biom12050641

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