Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization
Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization
About this item
Full title
Author / Creator
Zhao, Yu , Zhou, Yueqing , Zhang, Weipan , Liu, Mingzhe , Duan, Jun , Zhang, Xiaopeng , Ma, Qiwang , Wang, Yujia , Zhang, Yuzhen , Guo, Zhongliang , Zhang, Ting and Zuo, Wei
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Irreversible damage of the lung epithelium in idiopathic pulmonary fibrosis (IPF) patients causes high mortality worldwide, with no lung repair approaches available currently. Here we show that in murine and monkey models, the KRT5
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P63
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progenitor cells in airway basal layer can enter the alveolar area post fibrotic injury. Aided wi...
Alternative Titles
Full title
Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_44fc25e6634d4e2db21075e0fdd292d9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_44fc25e6634d4e2db21075e0fdd292d9
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-56501-w