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Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization

Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_44fc25e6634d4e2db21075e0fdd292d9

Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization

About this item

Full title

Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2025-02, Vol.16 (1), p.1303-16, Article 1303

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Irreversible damage of the lung epithelium in idiopathic pulmonary fibrosis (IPF) patients causes high mortality worldwide, with no lung repair approaches available currently. Here we show that in murine and monkey models, the KRT5
+
 P63
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progenitor cells in airway basal layer can enter the alveolar area post fibrotic injury. Aided wi...

Alternative Titles

Full title

Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_44fc25e6634d4e2db21075e0fdd292d9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_44fc25e6634d4e2db21075e0fdd292d9

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-025-56501-w

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