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Single-Cell Transcriptomics and In Vitro Lineage Tracing Reveals Differential Susceptibility of Huma...

Single-Cell Transcriptomics and In Vitro Lineage Tracing Reveals Differential Susceptibility of Huma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4514585e6d484764b01803e2bda5c805

Single-Cell Transcriptomics and In Vitro Lineage Tracing Reveals Differential Susceptibility of Human iPSC-Derived Midbrain Dopaminergic Neurons in a Cellular Model of Parkinson's Disease

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Full title

Single-Cell Transcriptomics and In Vitro Lineage Tracing Reveals Differential Susceptibility of Human iPSC-Derived Midbrain Dopaminergic Neurons in a Cellular Model of Parkinson's Disease

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2023-12, Vol.12 (24), p.2860

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

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Scope and Contents

Contents

Advances in stem cell technologies open up new avenues for modelling development and diseases. The success of these pursuits, however, relies on the use of cells most relevant to those targeted by the disease of interest, for example, midbrain dopaminergic neurons for Parkinson's disease. In the present study, we report the generation of a human in...

Alternative Titles

Full title

Single-Cell Transcriptomics and In Vitro Lineage Tracing Reveals Differential Susceptibility of Human iPSC-Derived Midbrain Dopaminergic Neurons in a Cellular Model of Parkinson's Disease

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Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4514585e6d484764b01803e2bda5c805

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4514585e6d484764b01803e2bda5c805

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells12242860

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