Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome
About this item
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Author / Creator
Hartlieb, Sabine A. , Sieverling, Lina , Nadler-Holly, Michal , Ziehm, Matthias , Toprak, Umut H. , Herrmann, Carl , Ishaque, Naveed , Okonechnikov, Konstantin , Gartlgruber, Moritz , Park, Young-Gyu , Wecht, Elisa Maria , Savelyeva, Larissa , Henrich, Kai-Oliver , Rosswog, Carolina , Fischer, Matthias , Hero, Barbara , Jones, David T. W. , Pfaff, Elke , Witt, Olaf , Pfister, Stefan M. , Volckmann, Richard , Koster, Jan , Kiesel, Katharina , Rippe, Karsten , Taschner-Mandl, Sabine , Ambros, Peter , Brors, Benedikt , Selbach, Matthias , Feuerbach, Lars and Westermann, Frank
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Telomere maintenance by telomerase activation or alternative lengthening of telomeres (ALT) is a major determinant of poor outcome in neuroblastoma. Here, we screen for ALT in primary and relapsed neuroblastomas (
n
= 760) and characterize its features using multi-omics profiling. ALT-positive tumors are molecularly distinct from other neuro...
Alternative Titles
Full title
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome
Authors, Artists and Contributors
Author / Creator
Sieverling, Lina
Nadler-Holly, Michal
Ziehm, Matthias
Toprak, Umut H.
Herrmann, Carl
Ishaque, Naveed
Okonechnikov, Konstantin
Gartlgruber, Moritz
Park, Young-Gyu
Wecht, Elisa Maria
Savelyeva, Larissa
Henrich, Kai-Oliver
Rosswog, Carolina
Fischer, Matthias
Hero, Barbara
Jones, David T. W.
Pfaff, Elke
Witt, Olaf
Pfister, Stefan M.
Volckmann, Richard
Koster, Jan
Kiesel, Katharina
Rippe, Karsten
Taschner-Mandl, Sabine
Ambros, Peter
Brors, Benedikt
Selbach, Matthias
Feuerbach, Lars
Westermann, Frank
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_451b2c4a26e94327b98d615c78ab75da
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_451b2c4a26e94327b98d615c78ab75da
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21247-8
