Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5...
Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis
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Author / Creator
Monsivais, Diana , Nagashima, Takashi , Prunskaite-Hyyryläinen, Renata , Nozawa, Kaori , Shimada, Keisuke , Tang, Suni , Hamor, Clark , Agno, Julio E. , Chen, Fengju , Masand, Ramya P. , Young, Steven L. , Creighton, Chad J. , DeMayo, Francesco J. , Ikawa, Masahito , Lee, Se-Jin and Matzuk, Martin M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
During early pregnancy in the mouse, nidatory estrogen (E2) stimulates endometrial receptivity by activating a network of signaling pathways that is not yet fully characterized. Here, we report that bone morphogenetic proteins (BMPs) control endometrial receptivity via a conserved activin receptor type 2 A (ACVR2A) and SMAD1/5 signaling pathway. Mi...
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Full title
Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_452a27be48ce4c76be17ee15253636c3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_452a27be48ce4c76be17ee15253636c3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-23571-5
