Lewis Acid-Facilitated Radiofluorination of MN3PU: A LRRK2 Radiotracer
Lewis Acid-Facilitated Radiofluorination of MN3PU: A LRRK2 Radiotracer
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Background: Temperature-sensitive radiopharmaceutical precursors require lower reaction temperatures (<100 °C) during nucleophilic radiofluorination in order to avoid compound thermolysis, often resulting in sub-optimal radiochemical yields (RCYs). To facilitate nucleophilic aromatic substitution (SNAr) of nucleofuges commonly used in radiofluorina...
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Lewis Acid-Facilitated Radiofluorination of MN3PU: A LRRK2 Radiotracer
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TN_cdi_doaj_primary_oai_doaj_org_article_452ee256a43b484dacfdf91a5c5b328a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_452ee256a43b484dacfdf91a5c5b328a
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules25204710
