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HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_456c8846a24d43e285fe7f27625f205f

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal

About this item

Full title

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-05, Vol.8 (1), p.8492-15, Article 8492

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Peritoneal fibrosis is a pathological alteration of the peritoneal membrane occurring in a variety of conditions including peritoneal dialysis (PD), post-surgery adhesions and peritoneal metastases. The acquisition of invasive and pro-fibrotic abilities by mesothelial cells (MCs) through induction of MMT, a cell-specific form of EMT, plays a main r...

Alternative Titles

Full title

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_456c8846a24d43e285fe7f27625f205f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_456c8846a24d43e285fe7f27625f205f

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-26319-2

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