The metalloproteinase PAPP-A is required for IGF-dependent chondrocyte differentiation and organizat...
The metalloproteinase PAPP-A is required for IGF-dependent chondrocyte differentiation and organization
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Insulin-like growth factor (IGF) signaling is required for proper growth and skeletal development in vertebrates. Consequently, its dysregulation may lead to abnormalities of growth or skeletal structures. IGF is involved in the regulation of cell proliferation and differentiation of chondrocytes. However, the availability of bioactive IGF may be c...
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Full title
The metalloproteinase PAPP-A is required for IGF-dependent chondrocyte differentiation and organization
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TN_cdi_doaj_primary_oai_doaj_org_article_45aba06494fa43148864fd55ae942a88
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_45aba06494fa43148864fd55ae942a88
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-71062-6
