CBFA2T3-GLIS2 mediates transcriptional regulation of developmental pathways through a gene regulator...
CBFA2T3-GLIS2 mediates transcriptional regulation of developmental pathways through a gene regulatory network
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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CBFA2T3-GLIS2
is a fusion oncogene found in pediatric acute megakaryoblastic leukemia that is associated with a poor prognosis. We establish a model of CBFA2T3-GLIS2 driven acute megakaryoblastic leukemia that allows the distinction of fusion specific changes from those that reflect the megakaryoblast lineage of this leukemia. Using this model,...
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CBFA2T3-GLIS2 mediates transcriptional regulation of developmental pathways through a gene regulatory network
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TN_cdi_doaj_primary_oai_doaj_org_article_45c7225d2e02401ea3d4836db5bb3be1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_45c7225d2e02401ea3d4836db5bb3be1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-53158-9
