Intracellular mGluR5 plays a critical role in neuropathic pain
Intracellular mGluR5 plays a critical role in neuropathic pain
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Spinal mGluR5 is a key mediator of neuroplasticity underlying persistent pain. Although brain mGluR5 is localized on cell surface and intracellular membranes, neither the presence nor physiological role of spinal intracellular mGluR5 is established. Here we show that in spinal dorsal horn neurons >80% of mGluR5 is intracellular, of which ∼60% is lo...
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Intracellular mGluR5 plays a critical role in neuropathic pain
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TN_cdi_doaj_primary_oai_doaj_org_article_45ca321373524d27b5c7dedf94d4f290
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_45ca321373524d27b5c7dedf94d4f290
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10604
